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pentobarbital will decrease the level or effect of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Double brexpiprazole dose over one-two weeks if administered with a robust CYP3A4 inducer.Contraindicated (1)pentobarbital will lower the extent or effect of doravirine by impacting hepatic/intest